Olverembatinib (dimesylate)
Catalogue number:
HY-15666A-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1421783-64-3
Purity:
99.81
Molecular Formula:
C31H35F3N6O7S2
Molecular Weight:
724.77
Alternative Names:
GZD824 (dimesylate); HQP1351 (dimesylate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Olverembatinib (GZD824) dimesylate is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib dimesylate potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib dimesylate strongly inhibits native Bcr-Abl and Bcr-AblT315I with IC50s of 0.34 nM and 0.68 nM, respectively. Olverembatinib dimesylate has antitumor activity[1]. Olverembatinib (dimesylate) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)