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Ganglioside GT1b (porcine) (ammonium salt)

Catalogue number:
CAY31592-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£498.00 Estimated delivery Tue 6 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

59247-13-1

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

2180.5

Alternative Names:

ganglioside gt1b, triammonium salt, ganglioside g1, trisialoganglioside gt1b

Product Description:

A mixture of porcine ganglioside GT1b with primarily C18:0 fatty acyl chain lengths, as well as a lower amount of C20:0 fatty acyl chain lengths, among various others; characterized by having two sialic residues linked to the inner galactose unit; binds to the neurotoxins BTxA, BTxA heavy chain, and tetanus toxin (IC50s = 11, 0.74, and 7.2 µM, respectively); ganglioside GT1b-containing liposomes can bind to the major coat protein VP1 from MCPyV; a putative MCPyV receptor; decreases spontaneous production of IL-6, IL-10, IgG, IgM, and IgA in human PBMCs by 31.4, 30.5, 60, 59.5, and 58%, respectively, at 10 µM

Storage Temperature:

-20°C

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