Ganglioside GM1 (ovine) (ammonium salt)
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1007119-81-4
≥98%
A solid
1563.9
1-o-[o-β-d-galactopyranosyl-(1→3)-o-2-(acetylamino)-2-deoxy-β-d-galactopyranosyl-(1→4)-o-[n-acetyl-α-neuraminosyl-(2→3)]-o-β-d-galactopyranosyl-(1→4)-β-d-glucopyranosyl]-ceramide, monoammonium salt, gm1 mixture, monosialoganglioside gm1 mixture
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- MSDS: View or download
A mixture of ganglioside GM1 species isolated from ovine brain with primarily C18:0 fatty acyl chain lengths, among various others; enriched in lipid rafts; associates with growth factor receptors and is required for TrkA expression on the cell surface; interacts with other proteins to increase calcium influx, affecting various calcium-dependent processes, including inducing neuronal outgrowth during differentiation; acts as a receptor for cholera toxin and the heat-labile enterotoxin from E. coli; accumulates in neurons in ganglioside GM1 gangliosidosis; levels are decreased in the substantia nigra pars compacta in postmortem brain from patients with Parkinson’s disease
-20°C