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NGI 1

Catalogue number:
CAY31519-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£102.00 Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

790702-57-7

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

394.5

Alternative Names:

5-[(dimethylamino)sulfonyl]-n-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide, n-linked glycosylation inhibitor 1

Product Description:

An OST inhibitor; binds to and stabilizes the STT3B catalytic subunit of OST in a CETSA; inhibits N-linked glycosylation in a reporter assay using D54 ER-LucT cells (IC50 = 1.1 µM); reduces glycosylation and membrane localization of EGFR in H3255 lung adenocarcinoma cells and inhibits proliferation of PC-9 and A549 NSCLC cells at 10 µM; inhibits dengue and Zika virus replication in HEK293 cells (EC50s = 0.85 and 2.2 µM, respectively); reduces viral RNA in HEK293 cells infected with West Nile virus or yellow fever virus

Storage Temperature:

-20°C

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