BMS 1166
Catalogue number:
CAY31441-10 mg
Supplier:
Size:
10 mg
Product is available in:
£681.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1818314-88-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
641.1
Alternative Names:
(4r)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl]-4-hydroxy-d-proline
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the protein-protein interaction between PD-1 and PDL1 (IC50 = 1.4 nM in a HTRF assay); increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1 (EC50 = 276 nM in a reporter assay)
Storage Temperature:
-20°C