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TGN 020

Catalogue number:
CAY30955-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£112.00 Estimated delivery Tue 6 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

51987-99-6

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

206.2

Alternative Names:

n-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide

Product Description:

An AQP4 inhibitor (IC50 = 3.1 µM in X. laevis oocytes transfected with AQP4); reduces brain edema and cortical infarction size in a mouse model of MCAO-induced transient focal cerebral ischemia at 200 mg/kg; reduces BALF IL-1α, IL-1β, IL-6, TNF-α, IL-23, and IL-17A levels and neutrophil infiltration, as well as increases survival, in a mouse model of LPS-induced acute lung injury at 200 mg/kg every 6 hours

Storage Temperature:

-20°C

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