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Succinobucol

Catalogue number:
CAY30886-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£107.00 Estimated delivery Tue 6 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

216167-82-7

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Weight:

616.9

Alternative Names:

butanedioic acid, 1-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenyl] ester, agi-1067, probucol monosuccinate

Product Description:

A probucol derivative with diverse biological activities; inhibits hydrogen peroxide-induced oxidation of the redox-sensitive dye H2DCF in HPAECs and U937 cells at 5 and 10 µM; reduces LPS-induced production of IL-6, IL-1β, and TNF-α in PBMCs from 0.3-10 µM; lowers plasma LDL levels and increases HDL levels in hypercholesterolemic cynomolgus monkeys at 50 and 100 mg/kg; inhibits the formation of aortic atherosclerotic plaques in ApoE-/- or Ldlr-/- mice

Storage Temperature:

-20°C

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