£601.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2239273-34-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
426.5
Alternative Names:
3-[2-amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1h-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methyl-benzonitrile
- Data sheet: View or download
- MSDS: View or download
Product Description:
An adenosine A2A and A2B receptor dual antagonist; inhibits the ability of adenosine to suppress activation of human CD4 or CD8 T cells, as well as monocyte-derived dendritic cells, in vitro; reduces tumor growth in an AT3-OVA syngeneic mouse model alone or in combination with doxorubicin; acts synergistically with an anti-PD-1 antibody to reduce tumor growth in a B16/F10 syngeneic mouse model
Storage Temperature:
-20°C