4-Aminosalicylic Acid
Catalogue number:
CAY33449-250 g
Supplier:
Size:
250 g _$$_
Product is available in:
£112.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
65-49-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
153.1
Alternative Names:
4-amino-2-hydroxy-benzoic acid, p-aminosalicylic acid, 4-asa, nsc 2083, nsc 211698, pas, sanipirol-4
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PABA antimetabolite with antibacterial activity; active against streptomycin-sensitive and -resistant strains of M. tuberculosis (MICs = 0.78 and 0.39 µg/ml, respectively); an alternative substrate for FolP1 and misincorporation into the folate pathway leads to accumulation of several folate-dependent metabolites including serine, homocysteine, dUMP, and AICAR, markers of folate pathway inhibition, in a concentration-dependent manner; reverses manganese-induced increases in rat hippocampal levels of NLRP3, cleaved caspase-1, and phosphorylated p65 at 300 mg/kg; a synthetic building block
Storage Temperature:
-20°C