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3,8'-Biapigenin

Catalogue number:
CAY34143-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£81.00 Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

101140-06-1

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

538.5

Alternative Names:

5,5′,7,7′-tetrahydroxy-2,2′-bis(4-hydroxyphenyl)-[3,8′-bi-4h-1-benzopyran]-4,4′-dione, 3,8"-biapigenin, i3,ii8-biapigenin

Product Description:

A biflavonoid with diverse biological activities; inhibits PTP1B (IC50 = 4.5 µM) and stimulates glucose uptake in 3T3-L1 cells at 5 and 10 µM; inhibits CYP3A4, CYP2C9, and CYP1A2 (Kis = 0.038, 0.32, and 0.95 µM, respectively); reverses kainiate and NMDA-induced cell death in isolated rat embryonic hippocampal neurons at 10 µM; decreases carrageenan-induced paw edema and protects against indomethacin-induced gastric lesions in rats at 8 mg/kg

Storage Temperature:

-20°C

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