KRAS inhibitor-9
Catalogue number:
HY-137497-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
300809-71-6
Purity:
99.85
Molecular Weight:
292.81
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 µM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)