(5Z,2E)-CU-3
Catalogue number:
HY-121638A-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1815598-71-0
Purity:
98.04
Molecular Weight:
392.47
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
(5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 µM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)