This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1184843-57-9
Purity:
98.53
Molecular Weight:
382.85
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50 of 13.3 nM for human CHK1. SAR-020106 shows excellent selectivity over CHK2. SAR-020106 significantly enhances the cell killing of Gemcitabine and SN38 by 3- to 29-fold in several colon tumor lines and in a p53-dependent fashion. SAR-020106 can enhance antitumor activity with selected anticancer agents[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)