This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
724711-21-1
Purity:
99.7
Molecular Weight:
340.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MK2-IN-3 is a potent and selective inhibitor of MAPKAP-K2 (MK-2), with an IC50 of 8.5 nM. MK2-IN-3 shows selectivity for MK-2 over MK-3, MK-5, ERK2, MNK1, p38a (IC50s=0.21, 0.081, 3.44, 5.7, and >100 µM, respectively) and MSK1, MSK2, CDK2, JNK2, IKK2 (IC50s>200 µM). MK2-IN-3 can reduce TNFα production in both U937 cells and in vivo[1].
Storage Temperature:
4°C (Powder, protect from light)