This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1126721-79-6
Molecular Formula:
C22H23D4FN4O2
Molecular Weight:
402.5
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Sunitinib-d4 is the deuterium labeled Sunitinib. Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2].