This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
120128-20-3
Purity:
98.39
Molecular Formula:
C25H21N5O2
Molecular Weight:
423.47
Alternative Names:
NID 525
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 µM.
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)