This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1197160-28-3
Purity:
98
Molecular Formula:
C25H28N8O3
Molecular Weight:
488.54
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PKI-179 is a potent and orally active dual PI3K/mTOR inhibitor, with IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR, respectively. PKI-179 also exhibits activity over E545K and H1047R, with IC50s of 14 nM and 11 nM, respectively. PKI-179 shows anti-tumor activity in vivo[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)