This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1255639-43-0
Purity:
96.48
Molecular Formula:
C26H21NO5
Molecular Weight:
427.45
Alternative Names:
TRB-N0224
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CMC2.24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 µM. CMC2.24 alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis[1][2][3].
Storage Temperature:
-20°C (Powder, protect from light)