This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2222635-15-4
Purity:
99.62
Molecular Formula:
C26H28F3N7O2
Molecular Weight:
527.54
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1+ pancreatic ductal adenocarcinoma (PDAC)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)