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(S)-Ro 32-0432

Catalogue number:
HY-108601A-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1781828-85-0

Molecular Formula:

C28H29ClN4O2

Molecular Weight:

489.01

Product Description:

(S)-Ro 32-0432 is a potent, selective, ATP-competitive and orally active PKC inhibitor. The IC50 values of (S)-Ro 32-0432 for PKCα, PKCβI, PKCβII, PKCγ and PKCε are 9.3 nM, 28 nM, 30 nM, 36.5 nM and 108.3 nM, respectively. (S)-Ro 32-0432 is also a selective G protein-coupled receptor kinase 5 (GRK5) inhibitor. (S)-Ro 32-0432 prevents T-cell activation and has the potential for chronic inflammatory and autoimmune diseases research[1][2].

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