This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2095486-67-0
Purity:
99.96
Molecular Formula:
C29H23BrClN5O2
Molecular Weight:
588.88
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 µM; Kd=0.043 µM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 µM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)