This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1217686-68-4
Purity:
99.11
Molecular Formula:
C42H37D8ClN6O5S2
Molecular Weight:
821.48
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ABT 737-d8 is the deuterium labeled ABT-737. ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)