Angiotensin (1-7) (acetate)
Catalogue number:
HY-12403A-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2855063-75-9
Purity:
99.87
Molecular Formula:
C43H66N12O13
Molecular Weight:
959.06
Alternative Names:
Ang-(1-7) (acetate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 µM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium[1][2][3].
Storage Temperature:
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)