BMSpep-57 (hydrochloride)
Catalogue number:
HY-P3143A-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
99.69
Molecular Formula:
C89H127ClN24O19S
Molecular Weight:
1904.63
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs[1].
Storage Temperature:
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)