This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2230731-99-2
Molecular Formula:
C15H25N5O2
Molecular Weight:
307.39
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- Protocol: View or download
Product Description:
KDOAM-25 is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells[1].