This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2166558-11-6
Purity:
99.95
Molecular Weight:
425.32
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7.1 nM; rP2X7: IC50=15 nM, Ki=2.9 nM). JNJ-55308942 is orally bioavailable, binds to brain P2X7 and blocks IL-1β release from adult rodent brain[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)