This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1072443-89-0
Purity:
98.47
Molecular Weight:
277.4
Alternative Names:
BML-258
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
SK1-I (BML-258), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 µM[1]. SK1-I shows no activity at SPHK1 PKCα, PKCδ, PKA, AKT1, ERK1, EGFR, CDK2, IKKβ or CamK2β. SK1-I enhances autophagy and has antitumor activity[2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)