This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2068818-02-8
Purity:
99.4
Molecular Weight:
409.5
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC50= 574 nM) that acts independently of Ca2+. NLRP3-IN-NBC6 inhibits Nigericin (HY-127019)-induced inflammasome activation in THP-1 cells and Imiquimod (HY-B0180)-induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)