This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1398496-82-6
Purity:
98.29
Molecular Weight:
365.38
Alternative Names:
S44819; Egis-13529
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)