Amitriptyline-d3 (hydrochloride)
Catalogue number:
HY-135096-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
342611-00-1
Purity:
99.46
Molecular Weight:
316.88
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Amitriptyline-d3 hydrochloride is the deuterium labeled Amitriptyline (hydrochloride). Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 µM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)