This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2366264-12-0
Molecular Weight:
341.45
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells[1].