RO2959 (monohydrochloride)
Catalogue number:
HY-113618B-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2309172-44-7
Purity:
98.21
Molecular Weight:
463.93
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)