Fluzoparib
Catalogue number:
HY-114778-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1358715-18-0
Purity:
99.85
Molecular Weight:
472.4
Alternative Names:
SHR3162; Fuzuloparib
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Fluzoparib (SHR3162) is a potent and orally active PARP1 inhibitor (IC50=1.46±0.72 nM, a cell‐free enzymatic assay) with superior antitumor activity. Fluzoparib selectively inhibits the proliferation of homologous recombination repair (HR)‐deficient cells, and sensitizes both HR‐deficient and HR‐proficient cells to cytotoxic agents. Fluzoparib exhibits good pharmacokinetic properties in vivo and can be used for BRCA1/2-mutant relapsed ovarian cancer research[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)