GW779439X
Catalogue number:
HY-103645-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
551919-98-3
Purity:
99.85
Molecular Weight:
454.45
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway[1][2]. MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)