This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
13060-14-5
Purity:
98
Molecular Weight:
446.49
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Yangambin, a furofuran lignan, is already isolated from plants such as member of the Annonaceae family, including species of the genus Rollinia: R. pickeli, R. exalbidaand R. mucosa, as well from the Magnolia biondii. Yangambin, a selective PAF receptor antagonist, inhibits Ca2+ influx through voltage-gated Ca2+ channels, leading to the reduction in [Ca2+]i in vascular smooth muscle cells and consequent peripheral vasodilation[1]. Yangambin exhibits the antiallergic activity against β-hexosaminidase release with an IC50 of 33.8 µM and for anti-inflammatory activity with an IC50 of 37.4 µM[2].
Storage Temperature:
4°C (Powder, protect from light)