This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
188791-09-5
Purity:
99.27
Molecular Weight:
597.36
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
JTE-607, a highly selective inflammatory cytokine synthesis inhibitor, protects from endotoxin shock in mice. JTE-607 inhibits inflammatory cytokine production, including TNF-α, IL-1β, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50s of 11, 5.9, 8.8, 7.3 and 9.1 nM, respectively[1]. Cleavage and Polyadenylation Specificity Factor 3 (CPSF3) is the target of JTE-607[2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)