IRE1α kinase-IN-1
Catalogue number:
HY-136735-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2328097-41-0
Purity:
99.44
Molecular Weight:
504.99
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. IRE1α kinase-IN-1 displays 100-fold selectivity for IRE1α over the IRE1β isoform. IRE1α kinase-IN-1 inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)