This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
192755-52-5
Purity:
98.75
Molecular Weight:
523.54
Alternative Names:
VX-740; HMR 3480
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active interleukin-1β converting enzyme (ICE, caspase 1) inhibitor with a Ki of 1.4 nM. Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)