Manzamine A (hydrochloride)
Catalogue number:
HY-117025A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
104264-80-4
Purity:
99.29
Molecular Weight:
585.22
Alternative Names:
Keramamine A (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 µM and 1.5 µM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1[1][2][3][4].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)