RWJ-56110 (dihydrochloride)
Catalogue number:
HY-108556A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2387505-58-8
Purity:
99.54
Molecular Weight:
863.65
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 µM) and thrombin (IC50=0.34 µM), quite selective relative to U46619 (HY-108566). RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell apoptosis[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)