RMC-5552
Catalogue number:
HY-132168-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2382768-62-7
Purity:
98.1
Molecular Weight:
1778.13
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)