This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2168525-92-4
Purity:
98.01
Molecular Weight:
356.27
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)