This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
591239-68-8
Purity:
98.47
Molecular Weight:
304.3
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 µM. ZINC05007751 shows antiproliferative activity against a panel of human cancer cell lines, and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity was observed against NEK2, NEK7, and NEK9[1].
Storage Temperature:
4°C (Powder, protect from light)