This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1609391-90-3
Purity:
99.62
Molecular Weight:
401.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tyk2-IN-7 is a TYK2 JH2 inhibitor, binds to TYK2 JH2 domain with IC50 and Ki.app of 0.00053 µM and 0.00007 µM, respectively. Tyk2-IN-7 provides a highly selective alternative to conventional TYK2 orthosteric inhibitors, inhibits TYK2/JAK1/JAK2 kinase domain. Tyk2-IN-7 provides robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)