GSK-872 (hydrochloride)
Catalogue number:
HY-101872A-25mg
Supplier:
Size:
25 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2703752-81-0
Purity:
99.64
Molecular Weight:
419.95
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 hydrochloride decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)