This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1644443-92-4
Purity:
98
Molecular Weight:
400.21
Alternative Names:
GW108X
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)