This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
423145-35-1
Purity:
98
Molecular Weight:
398.84
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 µM for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)