This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2641930-61-0
Purity:
98.08
Molecular Weight:
413.9
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
FNDR-20123 is a safe, first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25/29/2/11/282 nM, respectively.) and inhibits Class III HDAC isoforms at nanomolar concentrations[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)