This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1614245-70-3
Purity:
98.42
Molecular Weight:
440.49
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABAA positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABAA receptors containing α1/α2/α3/α5 subunits (Kis of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy[1].
Storage Temperature:
4°C (Powder, protect from light)