This product is for research use only and is not for human consumption or therapeutic use.
Purity:
95
Molecular Weight:
456.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative with enhanced the potency by 255-fold in the petit-LUBAC inhibition, and 10-fold and 4-fold in the LUBAC- and TNF-α-mediated NF-κB activation, respectively than HOIPIN-1. HOIPIN-1 is a promising tool to explore the cellular functions of LUBAC[1].
Storage Temperature:
-20°C (Powder, sealed storage, away from moisture and light)